Check out the companies making headlines in midday trading: Kohl’s — Shares tumbled 18% after the retailer cut its sales outlook amid an uncertain holiday backdrop . The latest quarter’s earnings and sales fell short of Wall Street analysts’ estimates, and the CEO will step down in January. Amgen — The biotech fell more than 3% after an experimental weight loss drug helped patients lose up to 20% of their weight after a year, the low end of investor expectations. Some analysts had been hoping for weight loss up to 25% in the phase two trial. Morgan Stanley — The Wall Street investment bank pulled back more than 2% after HSBC downgraded it to hold from buy, citing a less attractive risk-to-reward balance. Best Buy — The electronics retail chain slumped 7% after slashing its full-year sales forecast . Best Buy now expects comparable, same-store sales to pull back by 2.5% to 3.5%, worse than a prior forecast. Franklin Resources — The money manager sank more than 3% after federal prosecutors charged the former co-chief investment officer of its Western Asset Management subsidiary with fraud. Dana Inc. — Shares added 9% after the auto parts supplier named a new CEO and announced a restructuring, including the sale of its highway business and a $200 million cost-cutting campaign. Abercrombie & Fitch — Shares tumbled about 5% after the ap …