Check out some of the stocks making the biggest moves in midday trading. Ultragenyx Pharmaceutical – Shares cratered more than 40% after Ultragenyx announced that its bone disease drug setrusumab fell short of expectations in two trials. “Neither study achieved its primary endpoint of reduction in annualized clinical fracture rate compared to placebo or bisphosphonates,” the company said in a statement. Newmont , Freeport-McMoRan – Shares of miners fell alongside the prices of gold and silver in midday trading Monday. Newmont dropped more than 5%, while Freeport-McMoran slid 2%. The Global X Silver Miners ETF (SIL) shed more than 4%. Silver prices topped $80 per ounce in overnight trading and then tumbled more than 7% on Monday, while gold fell over 4%. Energy stocks – Energy companies saw their shares rise as oil prices climbed more than 2%. Investors considered the prospect of peace talks in Ukraine alongside the possibility of supply disruption in the Middle East. Shares of Diamondback Energy and Devon Energy popped nearly 2%, and the energy sector of the S & P 500 was the top gainer in the index. DigitalBridge — The private equity firm that invests in data centers and other assets popped 10% . Japan’s SoftBank announced Monday that it has entered an agreement to acquire DigitalBridge for $4 billion. Nvidia — The chipmak …