The AI industry entered 2025 with strong momentum.
There were 49 startups that raised funding rounds worth $100 million or more in 2024, per our count at TechCrunch; three companies raised more than one “mega-round,” and seven companies raised rounds that were $1 billion in size or larger.
The industry didn’t slow down in 2025. While less companies raised rounds larger than $1 billion, four — Anthropic raised two rounds over $1 billion — significantly more companies raised multiple rounds compared to 2024, eight.
How will 2026 compare? Elon Musk’s xAI announced a $20 billion Series E round and Sam Altman’s brain computer interface startup Merge Labs raised a $250 million seed round (with OpenAI as the lead investor) in the first few weeks of 2026, so signs point to another strong year. Of course, it’s still early; we’ll be watching to see if the momentum continues.
Here are all the U.S. AI companies that raised $100 million last year:
December:
Austin, Texas-based Mythic, which builds power-efficient compute for AI, raised a $125 million venture round that was led by DCVC. The round was announced on December 17 and included SoftBank, NEA and Linse Capital, among other investors.
Chai Discovery announced a $130 million Series B round on December 15. The round valued the company that builds AI models for biotech and drug discovery at $1.2 billion. Oak HC/FT and General Catalyst co-led the round.
Generative media platform Fal announced its third funding round of 2025 on December 9. This $140 million Series D round was led by Sequoia and valued the company at more than $4.5 billion.
Unconventional AI announced a monster $475 million seed round led by Lightspeed Venture Partners and Andreesen Horowitz on December 8. The round valued the one-year-old startup, which is rethinking the foundation of computers in the age of AI, at nearly $4.5 billion.
Boston-based 7AI, which builds cybersecurity AI agents, raised a $130 million Series A round that was announced on December 4. Index Ventures led the round with participation from Greylock, Spark Capital and CRV, among others.
November
All-in-one AI workspace platform Genspark announced a $275 million Series B round that valued the company at $1.25 billion on November 20. The round included Emergence Capital Partners, SBI Investment, and LG Technology Ventures, among others.
Luma AI, which builds models used for photo and video creation, raised $900 million in a Series C round that valued the startup at $4 billion. The round was led by Humain with participation from Andreessen Horowitz, AMD Ventures and Amplify Partners, among others.
Anysphere, the maker of viral vibe-coding platform Cursor, raised $2.3 billion in a funding round that valued the company at $29.3 billion. The round was announced on November 13 and is the company’s second funding round this year.
Parallel, which builds web infrastructure for AI agents, raised a $100 million Series A round that was announced on November 12. The round was co-led by Index Ventures and Kleiner Perkins.
Healthcare AI agent startup Hippocratic AI raised a $126 million Series C round that valued the company at $3.5 billion. The round w …