Over the past few years, there has been a steady influx of startups trying to treat issues like depression, period pain, PMS, anxiety and insomnia by using wearables that apply electrical, magnetic or ultrasonic signals to stimulate the brain.
San Francisco-based Mave Health is the latest of that fleet, and claims its $495, neuromodulation headset can improve attention and mood, regulate stress, and even measure mental health. The startup is positioning the wearable as a non-medical device so it won’t need clearance from agencies like the U.S. Food and Drug Administration (FDA) to sell in the U.S.
Dhawal Jain, who started the company in 2023 with his college batch mates Jai Sharma (CMO) and Aman Kumar (CTO), said he realized the need for such a device after his flatmate’s fiancée committed suicide during the COVID-19 pandemic lockdowns.
Founders Aman Kumar, Jai Sharma, and Dhawal Jain. Image Credits: Mave Health
“In India, committing suicide is a crime, which meant there was police involved, and we had to speak to her psychologist. The answers we got from them made us question if any of it made sense. We started connecting with other psychologists and were getting the same answers,” Jain said.
The founders felt that there was no tangible way to measure progress in the mental health space. “For example, if you ask a psychologist how do you know if a person is making progress, their response to it is very standard, which is that it’s not about progress. It’s about process […] But for somebody with depression who is spending a lot of time in therapy, progress is important. So how do you know whether they’re making progress or not? And even these basic questions were not being answered.”
In an effort to solve that, the team started to learn more about neuroscience by talking to experts, and soon after realized that while there has been progress around neuromodulation in labs, consumers haven’t had the benefit of it.
The company then worked with medical device and mental health experts to conduct trials of the technology. But eventually it took a different route and positioned its headset as a lifestyle device. Jain said this approach would let Mave reach a wider audience.
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The device and technology
Mave Health’s device employs transcranial direct current stimulation (tDCS), a non-invasive technique to administer low-intensity currents to the brain to fire up neurons. The technique is sometimes used in psychology, and is said to be safe. Side effects are mild and temporary, like itching or discomfort.
The headset delivers a low 1-2 mA current to stimulate the brain. The startup says customers can use the device, which weighs roughly 100 grams, anytime, and recommends daily sessions spanning 20 minutes for the first few weeks of usage.
The startup also provides an app that can measure long-term trends in mood, focus and stress levels. It can also integrate with other health data and track measures like Heart Rate Variability (HRV). Jain said users start with a self-reported baseline assessment when they start, and complete follow-up assessments every two to four weeks, which helps Mave understand if the device is helping a user in the long term.
Image Credits: Mave HealthImage Credits:Mave Health
The company hasn’t performed any clinical trials or published any studies yet. However, Jain says it worked with more than 500 users in a private beta in 2024 and 20 …