A Polymarket advertisement in a subway station in New York, US, on Thursday, Feb. 5, 2026. Michael Nagle | Bloomberg | Getty ImagesPrediction market platform Polymarket has completed its first block trade on an artificial intelligence compute infrastructure-related contract, the company shared exclusively with CNBC. The six-figure transaction was between FalconX, a digital asset brokerage, and Anera Labs, a trading technology startup. FalconX and Anera Labs traded on a contract related to the Ornn Compute Price Index, a benchmark that tracks Nvidia’s H100 GPU chip rental pricing. “Prediction markets are emerging as one of the most powerful venues for institutional block trades, and this transaction is proof,” said Brooke Rizzetto, head of institutional liquidity at Polymarket, in a statement. “Seeing an institutional counterparty use Polymarket to hedge real GPU compute exposure at scale is exactly the future we have been building toward.”Block trades are large, privately negotiated transactions that are typically executed outside of a public market to avoid price volatility. They are a regular occurrence with equities on big Wall Street trading desks.The announcement comes just over a month after Kalshi, Polymarket’s chief rival, completed the first block trade on any prediction market platform. However, Polymarket in a statement noted that this was the first institutional prediction market trade on-chain, as the company’s international platform operates on the Polygon blockchain. Shayne Coplan, chief executive officer of Polymarket, on the floor of the New York Stock Exchange (NYSE) in New York, US, on Thursday, Nov. 13, 2025. Michael Nagle | Bloomberg | Getty ImagesPolymarket’s international exchange is separate from its U.S. platform, which launched in December after it was prohibited from operating in the country in 2022 for not properly registering with regulators. The Commodity Futures Trading Commission — the federal regulator for prediction markets — and the Department of Justice in July dropped their investigations into the company without charges. The CFTC regulates Polymarket’s U.S. platform. While individual traders have led to prediction market vol …