Human Centipede director Tom Six reveals multiple sclerosis diagnosis in ‘final film’

by | Aug 8, 2026 | Entertainment

Human Centipede director Tom Six reveals multiple sclerosis diagnosis in ‘final film’

Tom Six, director of the 2009 horror film The Human Centipede, has disclosed that he has been diagnosed with multiple sclerosis and has spent the last six years confined to his Amsterdam apartment. In a documentary titled The End of Tom Six, which the filmmaker describes as his final work, he discusses how the neurological condition has affected his daily functioning and mobility.

Six initially gained recognition with The Human Centipede, an independently produced horror film that became a cultural reference point despite modest box office performance. He followed this with sequels released in 2011 and 2015. In 2018, Six produced a trailer for a film called The Onania Club, which he states failed to secure distribution.

According to Six’s account in the documentary, the stress surrounding his inability to find a distributor for The Onania Club significantly worsened his multiple sclerosis symptoms. Multiple sclerosis is a neurological disease affecting the brain and spinal cord, with symptoms varying among patients and potentially including fatigue, vision problems, mobility difficulties, and muscle complications.

The filmmaker details his daily routine as primarily consisting of rest in his home, accompanied by film viewing, smoking, and specific dietary choices. He notes he leaves his residence only for occasional nighttime visits to a nearby cafe. Six indicates he did not publicly disclose his diagnosis at the time it was made due to his resistance to being perceived as a victim.

The documentary, formatted as a pay-what-you-want release on YouTube as of 15 August, contains sections where Six addresses what he characterizes as industry challenges. His producer released a statement indicating that the extended period of stress related to distribution efforts for his film projects has significantly impacted Six’s health condition.

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