Check out the companies making the biggest moves premarket: AstraZeneca — The pharma giant rose 3% after its experimental drug, tozorakimab, was found to meaningfully reduce flare-ups in cases of chronic obstructive pulmonary disease. The drug delivered the results in two late-stage trials, and the company said full results will be delivered at an upcoming medical meeting. Tripadvisor — The travel booking website gained 3% following an upgrade to buy from neutral at Bank of America, citing accelerating activist engagement and rising strategic optionality across the portfolio. Argan — The construction firm rallied more than 10.5% after reporting fourth-quarter earnings and revenue that exceeded expectations. Argan posted earnings of $3.47 on revenue of $262.1 million. Analysts polled by FactSet forecasted per-share earnings of $1.98 on revenue of $255.3 million. Unity Software — The platform for game developers surged more than 11% after Unity Software issued preliminary first-quarter adjusted EBITDA of $130 million to $135 million, higher than previous guidance of $105 million to $110 million. Newsmax — Shares of the conservative cable news network jumped 5% after posting fourth-quarter revenue and full-year sales guidance that came in stronger than expected. Quarterly revenue of $52.2 million exceeded the $44.0 million FactSet consensus estimate. It forecast revenue of $212 million to $216 million for the year ending December, more than the $206.1 million est …
